S Pandey Lab, Department of Psychiatry, College of Medicine
Epigenetics of complex psychiatry disorders including drug and alcohol addiction, basic mechanisms of gene expression in the brain, novel treatments for addiction and other psychiatric disorders.
Kyzar E, Banerjee R. Targeted epigenetic modulation of gene expression in the brain. J Neurosci; 2016: In Press.
Kyzar E, Floreani C, Teppen T, Pandey S. Adolescent alcohol exposure: Burden of epigenetic reprogramming, synaptic remodeling, and adult psychopathology. Front Neurosci; 2016: 10:222.
Kyzar E, Zhang H, Sakharkar A, Pandey S. Adolescent alcohol exposure alters lysine demethylase 1 (LSD1) expression and histone methylation in the amygdala during adulthood. Addict Biol; 2016: In Press.
Homberg J, Kyzar E, Nguyen M, Norton W, Pittman J, Poudel M, Gaikwad S, Nakamura S, Koshiba M, Yamanouchi H, Scattoni M, Ullman J, Diamond D, Kaluyeva A, Parker M, Klimenko V, Apryatin S, Brown R, Song C, Gainetdinov R, Gottesman I, Kalueff A. Understanding autism and other neurodevelopmental disorders through experimental translational neurobehavioral models. Neurosci Biobehav Rev, 2016: 65:292-312.
Kyzar E, Pandey S. Molecular mechanisms of synaptic remodeling in alcoholism. Neurosci Lett; 2015; 601:11-9.
Kyzar E, Stewart A, Landsman S, Collins C, Gebhardt M, Robinson K. Kalueff A. Behavioral effects of bidirectional modulation of brain monoamines by reserpine and d-amphetamine in zebrafish. Brain Res; 2013, 1527:108-16.
Cachat J, Kyzar E, Collins C, Gaikwad S, Green J, Roth A, El-Ounsi M, Davis A, Pham M, Landsman S, Kalueff A. Unique and potent effects of acute ibogaine on zebrafish: the developing utility of aquatic models for hallucinogenic drug research. Behav Brain Res, 2013, 236:258-269.
Kyzar E, Pham M, Roth A, Cachat J, Green J, Gaikwad S, Kalueff A. Alterations in grooming activity and syntax in heterozygous SERT and BDNF knockout mice: the utility of behavior-recognition tools to characterize mutant mouse phenotypes. Brain Res Bull, 2012, 89:168-176.
Kyzar E, Collins C, Gaikwad S, Green J, Roth A, Monnig L, El-Ounsi M, Davis A, Freeman A, Capezio N, Stewart A, Kalueff A. Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology. Progress Neuro-psychopharmacol Biol Psychiatry, 2012; 37:194-202.
Riehl R, Kyzar E, Allain A, Green J, Hook M, Monnig L, Rhymes K, Roth A, Pham M, Razavi R, DiLeo J, Gaikwad S, Hart P, Kalueff A. Behavioral and physiological effects of acute ketamine exposure in adult zebrafish. Neurotoxicol Teratol, 2011; 33:658-667.
Kyzar E, Gaikwad S, Roth A, Green J, Pham M, Stewart A, Liang Y, Kobla V, Kalueff A. Towards high-throughput phenotyping of complex patterned behaviors in rodents: focus on mouse self grooming and its sequencing. Behav Brain Res, 2011; 225:426-431.