PhD, University of Washington
Associate Professor, Director of Graduate Studies, Department of Psychology, College of Liberal Arts & Sciences
Associate Director, Laboratory of Integrative Neuroscience, College of Liberal Arts & Sciences
Office: 1042C BSB
Phone: (312) 996-3113
Web Site: Mitchell Roitman Home Page
My lab is interested in understanding the neural circuits that encode affective (e.g. reward, aversion) information and convert that information into decisions to approach and consume or avoid and reject. We are particularly interested in the role of the neurotransmitter dopamine and neurons of the nucleus accumbens in these processes. Our goals are to understand normal, motivated behavior as well as disorders of motivation including obesity and drug addiction.
Fortin SM and Roitman MF (2018). Challenges to body fluid homeostasis differentially recruit phasic dopamine signaling in a taste-selective manner. Journal of Neuroscience; Pub ahead of print.
Cone, J.J., Fortin, S.M., McHenry, J.A., Stuber, G.D., McCutcheon, J.E. & Roitman, M.F. (2016) Physiological state gates acquisition and expression of mesolimbic reward prediction signals. Proceedings of the National Academy of Sciences, 113:1943-8.
Fortin, S.M., Chartoff, E.H. & Roitman, M.F. (2015) The aversive agent lithium chloride suppresses phasic dopamine release through central GLP-1 receptors. Neuropsychopharmacology, 41:906-15.
Cone, JJ, McCutcheon, JE & Roitman, MF. (2014) Ghrelin acts as an interface between physiological state and phasic dopamine signaling. Journal of Neuroscience, 34: 4905-13.
Daberkow DP, Brown HD, Pakdeeronachit S, Doellman MA, Ragozzino ME, Garris PA & Roitman MF. (2013) Paradoxical activation of exocytic dopamine release by amphetamine in the awake rat. The Journal of Neuroscience, 33: 452-463.
McCutcheon, JE, Ebner, SE, Loriaux, AL & Roitman, MF. (2012) Encoding of aversion by dopamine and the nucleus accumbens. Frontiers in Neuroscience, 6:137.