Constance Jeffery

PhD, University of California, Berkeley

Associate Professor, Department of Biological Sciences, College of Liberal Arts & Sciences

Office: 4252 MBRB

Lab: 4260 MBRB

Phone: 312-413-2516


Web Site: Constance Jeffery Departmental Page


Research Interests:

We use X-ray crystallography and other biophysical, biochemical, and bioinformatics methods to study the structures and functions of proteins. Current interests include moonlighting proteins, transmembrane receptors, and proteins involved in cancer and tuberculosis.



C. J. Jeffery. (2016) Protein Species and Moonlighting Proteins: Very Small Changes in a Protein’s Covalent Structure Can Change its Biochemical Function. Journal of Proteomics. pii: S1874-3919(15)30146-9. doi: 10.1016/j.jprot.2015.10.003.

W. Wang and C. J. Jeffery. (2016) An Analysis of Surface Proteomics Results Reveals Novel Candidates for Intracellular/Surface Moonlighting Proteins in Bacteria. Mol Biosyst. 2016 Apr 26;12(5):1420-31. doi: 10.1039/c5mb00550g. PMID: 26938107

Mani, M. C. Chen, V. Amblee, H. Liu, T. Mathur, G. Zwicke, S. Zabad, B. Patel, J. Thakkar, and C. J. Jeffery. (2015) Moonlighting Proteins Database (MoonProt): A database of proteins that are known to moonlight. Nucleic Acids Research. 43: D277–D282.

Amblee, V. and C. J. Jeffery.  (2015) Physical Features of Intracellular Proteins that Moonlight on the Cell Surface.  PLOS One. 10(6):e0130575. doi: 10.1371/journal.pone.0130575. eCollection 2015. PMID: 26110848