Chieh Chang

PhD, California Institute of Technology

Associate Professor, Department of Biological Sciences, College of Liberal Arts & Sciences

Office: 4072 MBRB


Phone: 312-413-9235


Web Site: Chieh Chang Laboratory Page


Research Interests:

Timing mechanisms for orderly neuronal connectivity in development and regeneration decline in aging.



Dong X, Chiu H, Park YJ, Zou W, Zou Y, Özkan E, Chang C*, Shen K*. (2016) “Precise regulation of the guidance receptor DMA-1 by KPC-1/Furin instructs dendritic branching decisions,” eLife, 5, e11008. *Co-corresponding authors

Ivakhnitskaia E*, Hamada K*, Chang C. (2016) “Timing Mechanisms in Neuronal Pathfinding, Synaptic Reorganization, and Neuronal Regeneration,” Development Growth & Differentiation, 58, 1-6. *Equal Contribution

Alqadah A, Hsieh Y-W, Vidal B, Chang C, Hobert O, Chuang CF. (2015) “Postmitotic diversification of olfactory neuron types is mediated by differential SOX-2 activities,” The EMBO Journal, 34, 2574-2589.

Chiu H, Alqadah A, Chang C. (2014) “The role of microRNAs in regulating neuronal connectivity,” Frontiers in Cellular Neuroscience, 7, 1-6.

Chiu H, Chang C. (2013) “Rejuvenating nerve cells in adults,” Aging, 5, 1-2.

Zou Y*, Chiu H*, Zinovyeva A, Ambros V, Chuang CF, Chang C. (2013) “Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers,” Science, 340, 372-376

*Equal Contribution

Recommended by Faculty of 1000; Featured in “Perspective: Heterochronic genes turn back the clock in old neurons” in Science.

Zou Y, Chiu H, Domenger D, Chuang CF, Chang C. (2012) “The lin-4 microRNA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction,” Science Signaling, 5, research article ra43.