PhD, McGill University
Assistant Professor, Department of Psychiatry, College of Medicine
Office: 464 SPH/PI
Web Site: Amynah Pradhan Departmental Page
Dr. Pradhan studies the neurobiology of opioid receptors. In particular her lab is interested in the role of opioid receptors in chronic pain and emotional disorders. She is also conducting research into the study of migraine. Her lab has developed animal models of chronic migraine and post-traumatic headache, and ongoing studies are focused on understanding the molecular and cellular mechanisms underlying these disorders.
A.A. Pradhan, Z. Bertels, S. Akerman. (2018) “Targeted Nitric Oxide Synthase Inhibitors for Migraine Neurotherapeutics.” Neurotherapeutics. 15(2):391-401.
L.S. Moye, M.L. Novack, A.F. Tipton, H. Krishnan, S.C. Pandey, A.A. Pradhan. (2018) “The development of a mouse model of mTBI-induced post-traumatic migraine, and identification of the delta opioid receptor as a novel therapeutic target.” Cephalalgia. Jan 1. epub ahead of print.
A. Vicente-Sanchez, I.J. Dripps, A.F. Tipton, H. Akbari, A. Akbari, E.M. Jutkiewicz, A.A. Pradhan. (2018) “Tolerance to high-internalizing delta opioid receptor agonist is critically mediated by arrestin 2.” British Journal of Pharmacology. May 3. epub ahead of print.
A.A. Pradhan, J. Perroy, W. Walwyn, M. Smith, A. Vicente-Sanchez, L. Segura, A. Bana, B. Kieffer, C. Evans. (2016) Agonist-selective recruitment of arrestin isoforms differentially modify delta opioid receptor function. Journal of Neuroscience. 36(12):3541–3551.
A.A. Pradhan, M. Smith, B. McGuire, I. Tarash, C. Evans, and A. Charles. (2014) Characterization of a Novel Model of Chronic Migraine. Pain 155(2):269-74.
A.A. Pradhan, M. Smith, J. Zyuzin, and A. Charles. (2014) Delta Opioid Receptor Agonists Inhibit Migraine-Related Pain, Aversive State, and Cortical Spreading Depression. British Journal of Pharmacology 171(9):2375-84.